8Y81
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity immunoglobulin epsilon receptor subunit alpha | polymer | 245 | 27830.2 | 1 | UniProt (P12371) Pfam (PF13895) | Rattus norvegicus (Norway rat) | Fc-epsilon RI-alpha,FcERI,IgE Fc receptor subunit alpha |
| 2 | B (B) | High affinity immunoglobulin epsilon receptor subunit beta | polymer | 243 | 26747.8 | 1 | UniProt (P13386) Pfam (PF04103) | Rattus norvegicus (Norway rat) | FcERI,Fc epsilon receptor I beta-chain,IgE Fc receptor subunit beta |
| 3 | C, F (C, G) | High affinity immunoglobulin epsilon receptor subunit gamma | polymer | 119 | 13459.3 | 2 | UniProt (P20411) Pfam (PF11628) Pfam (PF02189) | Rattus norvegicus (Norway rat) | Fc receptor gamma-chain,FcRgamma,Fc-epsilon RI-gamma,IgE Fc receptor subunit gamma,FceRI gamma |
| 4 | D, E (E, F) | Immunoglobulin heavy constant epsilon | polymer | 363 | 41815.4 | 2 | UniProt (P01855) Pfam (PF07654) Pfam (PF00047) | Rattus norvegicus (Norway rat) | Ig epsilon chain C region |
| 5 | G, H (D, H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | I (T) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | J, K, M, N, O (A, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 8 | L (B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (363416) PubChem (45489984) PubChem (500055) PubChem (60078761) PubChem (57163942) PubChem (73440805) PubChem (89891013) PubChem (13301926) PubChem (13301927) PubChem (99567469) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (137392566) PubChem (137496323) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (155804219) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (169132514) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
C, G: 1 - 86 (UniProt: P20411)
E, F: 95 - 429 (UniProt: P01855)
| PDB | External Database | Details |
|---|---|---|
| Gly 87 | - | expression tag |
| Ser 88 | - | expression tag |
| Gly 89 | - | expression tag |
| Trp 90 | - | expression tag |
| Ser 91 | - | expression tag |
| His 92 | - | expression tag |
| Pro 93 | - | expression tag |
| Gln 94 | - | expression tag |
| Phe 95 | - | expression tag |
| Glu 96 | - | expression tag |
| Lys 97 | - | expression tag |
| Gly 98 | - | expression tag |
| Ser 99 | - | expression tag |
| Gly 100 | - | expression tag |
| Asp 101 | - | expression tag |
| Tyr 102 | - | expression tag |
| Lys 103 | - | expression tag |
| Asp 104 | - | expression tag |
| Asp 105 | - | expression tag |
| Asp 106 | - | expression tag |
| Asp 107 | - | expression tag |
| Lys 108 | - | expression tag |
| Gly 109 | - | expression tag |
| Ser 110 | - | expression tag |
| Gly 111 | - | expression tag |
| Trp 112 | - | expression tag |
| Ser 113 | - | expression tag |
| His 114 | - | expression tag |
| Pro 115 | - | expression tag |
| Gln 116 | - | expression tag |
| Phe 117 | - | expression tag |
| Glu 118 | - | expression tag |
| Lys 119 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 73 | - | initiating methionine |
| Ser 74 | - | expression tag |
| Val 75 | - | expression tag |
| Pro 76 | - | expression tag |
| Thr 77 | - | expression tag |
| Gln 78 | - | expression tag |
| Val 79 | - | expression tag |
| Leu 80 | - | expression tag |
| Gly 81 | - | expression tag |
| Leu 82 | - | expression tag |
| Leu 83 | - | expression tag |
| Leu 84 | - | expression tag |
| Leu 85 | - | expression tag |
| Trp 86 | - | expression tag |
| Leu 87 | - | expression tag |
| Thr 88 | - | expression tag |
| Asp 89 | - | expression tag |
| Ala 90 | - | expression tag |
| Arg 91 | - | expression tag |
| Cys 92 | - | expression tag |
| Asp 93 | - | expression tag |
| Ile 94 | - | expression tag |
| His 430 | - | expression tag |
| His 431 | - | expression tag |
| His 432 | - | expression tag |
| His 433 | - | expression tag |
| His 434 | - | expression tag |
| His 435 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165127.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1597.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1592.8 | |
| All* | Total formula weight | 168317.7 |
