8Y7M

FluPol-NS2 complex (local refinement)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (E, A)	Polymerase acidic protein	polymer	729	84625.4	2	UniProt (P03434)	Influenza A virus (A/nt/60/1968(H3N2))	RNA-directed RNA polymerase subunit P2
2	B, E (F, B)	RNA-directed RNA polymerase catalytic subunit	polymer	757	86524.1	2	UniProt (Q910D6)	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)	Polymerase basic protein 1,PB1,RNA-directed RNA polymerase subunit P1
3	C, F (G, C)	Polymerase basic protein 2	polymer	792	89495.9	2	UniProt (P03429)	Influenza A virus (A/nt/60/1968(H3N2))	RNA-directed RNA polymerase subunit P3
4	G, H (I, J)	Nuclear export protein	polymer	121	14355.3	2	UniProt (Q910E4)	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)	NEP,Non-structural protein 2,NS2

Sequence modifications

E, A: 1 - 716 (UniProt: P03434)

PDB	External Database	Details
Met -12	-	initiating methionine
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

G, C: 1 - 759 (UniProt: P03429)

PDB	External Database	Details
Arg 691	Leu 691	engineered mutation
Gly 760	-	expression tag
Trp 761	-	expression tag
Ser 762	-	expression tag
His 763	-	expression tag
Pro 764	-	expression tag
Gln 765	-	expression tag
Phe 766	-	expression tag
Glu 767	-	expression tag
Lys 768	-	expression tag
Gly 769	-	expression tag
Gly 770	-	expression tag
Gly 771	-	expression tag
Ser 772	-	expression tag
Gly 773	-	expression tag
Gly 774	-	expression tag
Gly 775	-	expression tag
Ser 776	-	expression tag
Gly 777	-	expression tag
Gly 778	-	expression tag
Ser 779	-	expression tag
Ala 780	-	expression tag
Trp 781	-	expression tag
Ser 782	-	expression tag
His 783	-	expression tag
Pro 784	-	expression tag
Gln 785	-	expression tag
Phe 786	-	expression tag
Glu 787	-	expression tag
Lys 788	-	expression tag
Gly 789	-	expression tag
Arg 790	-	expression tag
Ser 791	-	expression tag
Gly 792	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	550001.5
All*	Total formula weight	550001.5

*Water molecules are not included.