8Y59
Crystal structure of TRIM21 PRYSPRY (D355A) in complex with (S)-hydroxyl-acepromazine.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase TRIM21 | polymer | 192 | 21597.2 | 1 | UniProt (P19474) Pfam (PF13765) Pfam (PF00622) | Homo sapiens (human) | 52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,RING finger protein 81,Ro(SS-A),Sjoegren syndrome type A antigen,SS-A,Tripartite motif-containing protein 21 |
| 2 | B (A) | (1~{S})-1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanol | non-polymer | 328.5 | 1 | Chemie (A1D5Y) | |||
| 3 | C (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 4 - 192 (UniProt: P19474)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Pro 2 | - | expression tag |
| Met 3 | - | expression tag |
| Ala 72 | Asp 355 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21597.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 328.5 | |
| All* | Total formula weight | 21925.7 |
