8Y4A
BA.2.86 S-trimer in complex with Nab XG2v046
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, C, A | Spike glycoprotein | polymer | 1204 | 133869.0 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | H, D | XG2v046 Heavy chain | polymer | 122 | 13547.2 | 2 | Homo sapiens (human) | ||
| 3 | L, E | XG2v046 Light chain | polymer | 108 | 11632.0 | 2 | Homo sapiens (human) | ||
| 4 | F, G, I, M, N... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 383.3 | 9 | In PDB GlyTouCan (G90333CG) | |||
| 5 | J, P, Q, U | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 6 | K | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(8-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB | |||
| 7 | B, A, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 39 | Chemie (NAG) |
Sequence modifications
B, C, A: 0 - 1208 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | insertion |
| Pro 17 | - | insertion |
| Leu 18 | - | insertion |
| Phe 19 | - | insertion |
| Ile 22 | Thr 19 | conflict |
| Thr 24 | Arg 21 | conflict |
| - | Leu 24 | deletion |
| - | Pro 25 | deletion |
| - | Pro 26 | deletion |
| Ser 27 | Ala 27 | variant |
| Leu 50 | Ser 50 | conflict |
| - | His 69 | deletion |
| - | Val 70 | deletion |
| Phe 127 | Val 127 | conflict |
| Asp 143 | Gly 142 | conflict |
| - | Tyr 145 | deletion |
| Ser 157 | Phe 157 | conflict |
| Gly 158 | Arg 158 | variant |
| - | Asn 211 | deletion |
| Ile 212 | Leu 212 | variant |
| Gly 213 | Val 213 | conflict |
| Phe 216 | Leu 216 | conflict |
| Asn 245 | His 245 | conflict |
| Asp 264 | Ala 264 | conflict |
| Val 332 | Ile 332 | conflict |
| His 339 | Gly 339 | conflict |
| Thr 356 | Lys 356 | conflict |
| Phe 371 | Ser 371 | conflict |
| Pro 373 | Ser 373 | conflict |
| Phe 375 | Ser 375 | conflict |
| Ala 376 | Thr 376 | conflict |
| Lys 403 | Arg 403 | conflict |
| Asn 405 | Asp 405 | conflict |
| Ser 408 | Arg 408 | conflict |
| Asn 417 | Lys 417 | conflict |
| Lys 440 | Asn 440 | conflict |
| His 445 | Val 445 | conflict |
| Ser 446 | Gly 446 | conflict |
| Asp 450 | Asn 450 | conflict |
| Trp 452 | Leu 452 | conflict |
| Lys 460 | Asn 460 | conflict |
| Asn 477 | Ser 477 | conflict |
| Lys 478 | Thr 478 | conflict |
| Lys 481 | Asn 481 | conflict |
| - | Val 483 | deletion |
| Lys 484 | Glu 484 | conflict |
| Pro 486 | Phe 486 | conflict |
| Arg 498 | Gln 498 | conflict |
| Tyr 501 | Asn 501 | conflict |
| His 505 | Tyr 505 | conflict |
| Lys 554 | Glu 554 | conflict |
| Val 570 | Ala 570 | conflict |
| Gly 614 | Asp 614 | conflict |
| Ser 621 | Pro 621 | conflict |
| Tyr 655 | His 655 | conflict |
| Lys 679 | Asn 679 | conflict |
| Arg 681 | Pro 681 | conflict |
| Ala 683 | Arg 683 | conflict |
| Ala 685 | Arg 685 | conflict |
| Lys 764 | Asn 764 | conflict |
| Tyr 796 | Asp 796 | conflict |
| Pro 817 | Phe 817 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Phe 939 | Ser 939 | conflict |
| Pro 942 | Ala 942 | conflict |
| His 954 | Gln 954 | conflict |
| Lys 969 | Asn 969 | conflict |
| Pro 986 | Lys 986 | variant |
| Pro 987 | Val 987 | variant |
| Leu 1143 | Pro 1143 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 451965.2 | |
| Branched | Number of molecules | 14 |
| Total formula weight | 5734.3 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 8627.1 | |
| All* | Total formula weight | 466326.6 |
