8Y3H
Cryo-EM structure of dengue virus serotype 2 strain D2Y98P-PP1 N153Q mutant in complex with human antibody 2D22 Fab at 37 deg C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Envelope protein | polymer | 495 | 54300.6 | 3 | UniProt (A0A678XB23) UniProt (by SIFTS) (A0A0S2PZC9) | dengue virus type 2 | Genome polyprotein |
| 2 | B, D, F (B, D, F) | Membrane polyprotein | polymer | 75 | 8384.8 | 3 | UniProt (A4GVG9) UniProt (by SIFTS) (A0A482JI47) | dengue virus type 2 | Genome polyprotein |
| 3 | G, I, K (G, I, K) | Human antibody 2D22 Fab heavy chain | polymer | 128 | 13805.5 | 3 | Homo sapiens | ||
| 4 | H, J, L (H, J, L) | Human antibody 2D22 Fab light chain | polymer | 115 | 12090.3 | 3 | Homo sapiens | ||
| 5 | M, N, O (A, C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, C, E: 1 - 495 (UniProt: A0A678XB23)
| PDB | External Database | Details |
|---|---|---|
| Gln 153 | Asn 153 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 265743.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 266407.3 |
