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8Y2M

Cryo-EM structure of the FB1-bound Lac1-Lip1 complex

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Ceramide synthase LAC1polymer42850289.12UniProt (P28496)
Pfam (PF03798)
Saccharomyces cerevisiae S288C (Baker's yeast)Very-long-chain ceramide synthase LAC1
2B, D
(B, D)
Ceramide synthase subunit LIP1polymer15017228.72UniProt (Q03579)Saccharomyces cerevisiae S288C (Baker's yeast)LAG1/LAC1-interacting protein 1
3E, H, I, J, M...
(A, B, C, D)
(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDEnon-polymer763.16Chemie (6PL)
4F, K
(A, C)
(2~{R})-2-[2-[(5~{R},6~{R},7~{S},9~{S},11~{R},16~{R},18~{S},19~{S})-19-azanyl-6-[(3~{R})-3-carboxy-5-oxidanyl-5-oxidanylidene-pentanoyl]oxy-5,9-dimethyl-11,16,18-tris(oxidanyl)icosan-7-yl]oxy-2-oxidanylidene-ethyl]butanedioic acidnon-polymer721.82Chemie (A1D5V)
5G, L
(A, C)
hexacosanoic acidnon-polymer396.72Chemie (7PO)
Sequence modifications
A, C: 1 - 418 (UniProt: P28496)
PDBExternal DatabaseDetails
Leu 419-expression tag
Glu 420-expression tag
Asp 421-expression tag
Tyr 422-expression tag
Lys 423-expression tag
Asp 424-expression tag
Asp 425-expression tag
Asp 426-expression tag
Asp 427-expression tag
Lys 428-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight135035.5
Non-Polymers*Number of molecules10
Total formula weight6815.6
All*Total formula weight141851.2
*Water molecules are not included.

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PDB entries from 2026-01-28

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