8Y2L
The Crystal Structure of Glucosyltransferase TcdB from Clostridioides difficile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glucosyltransferase TcdB | polymer | 546 | 63164.6 | 3 | UniProt (P18177) | Clostridioides difficile | |
| 2 | D, F, H (A, B, C) | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) PubChem (27854) | |||
| 3 | E, G, I (A, B, C) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 3 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) | |||
| 4 | J, K, L (A, B, C) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 543 (UniProt: P18177)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Cys 59 | Tyr 59 | engineered mutation |
| Gly 244 | Glu 244 | engineered mutation |
| Ala 542 | Ser 542 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 189493.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1377.3 | |
| All* | Total formula weight | 190871.0 |
