8Y2G
Cryo-EM structure of human dopamine transporter in complex with methylphenidate
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium-dependent dopamine transporter | polymer | 562 | 62451.4 | 1 | UniProt (Q01959) Pfam (PF00209) | Homo sapiens (human) | DA transporter,DAT,Solute carrier family 6 member 3 |
| 2 | B (A) | Dexmethylphenidate | non-polymer | 233.3 | 1 | Chemie (A1D5U) | |||
| 3 | C, D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) |
Sequence modifications
A: 59 - 620 (UniProt: Q01959)
| PDB | External Database | Details |
|---|---|---|
| Val 67 | Ile 67 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62451.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 757.2 | |
| All* | Total formula weight | 63208.6 |
