8Y1U
Crystal structure of ASB7-Elongin B/C bound to the LZTS1-degron
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ankyrin repeat and SOCS box protein 7 | polymer | 309 | 34835.8 | 1 | UniProt (Q9H672) Pfam (PF12796) Pfam (PF07525) | Homo sapiens (human) | ASB-7 |
| 2 | B (B) | Peptide from Leucine zipper putative tumor suppressor 1 | polymer | 23 | 2900.3 | 1 | UniProt (Q9Y250) | Homo sapiens | F37/esophageal cancer-related gene-coding leucine-zipper motif,Fez1 |
| 3 | C (C) | Elongin-B | polymer | 104 | 11748.4 | 1 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 4 | D (D) | Elongin-C | polymer | 96 | 10843.4 | 1 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 11 - 318 (UniProt: Q9H672)
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60327.9 | |
| All* | Total formula weight | 60327.9 |
