8Y1P

Cryo-EM structure of human ABCA7 in DOPS-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Phospholipid-transporting ATPase ABCA7	polymer	2146	234598.6	1	UniProt (Q8IZY2) Pfam (PF12698) Pfam (PF00005) Pfam (PF23321)	Homo sapiens (human)	ABCA-SSN,ATP-binding cassette sub-family A member 7,Autoantigen SS-N,Macrophage ABC transporter
2	B, C (A)	O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine	non-polymer		788.0	2	Chemie (17F)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	234598.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1576.1
All*	Total formula weight	236174.7

*Water molecules are not included.