8Y0Q
Complex of FMDV O/18074 and inter-serotype broadly neutralizing antibodies pOA-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | VP1 of capsid protein | polymer | 213 | 23686.8 | 1 | UniProt (A0A1P8DYS7) Pfam (PF22663) | Foot-and-mouth disease virus O | |
| 2 | B (2) | VP2 of capsid protein | polymer | 218 | 24350.4 | 1 | UniProt (J9PGT1) Pfam (PF00073) | Foot-and-mouth disease virus O | |
| 3 | C (3) | VP3 of capsid protein | polymer | 220 | 23886.8 | 1 | UniProt (A0A1C6ZW66) Pfam (PF00073) | Foot-and-mouth disease virus O | |
| 4 | D (4) | VP4 of capsid protein | polymer | 85 | 8862.2 | 1 | UniProt (J9PGT1) Pfam (PF08935) | Foot-and-mouth disease virus O | |
| 5 | E (H) | pOA2 VH | polymer | 123 | 13721.4 | 1 | Sus scrofa | ||
| 6 | F (L) | pOA2 VL | polymer | 109 | 11587.9 | 1 | Sus scrofa |
Sequence modifications
1: 1 - 213 (UniProt: A0A1P8DYS7)
2: 1 - 218 (UniProt: J9PGT1)
3: 1 - 220 (UniProt: A0A1C6ZW66)
| PDB | External Database | Details |
|---|---|---|
| Thr 33 | Ala 33 | conflict |
| Glu 47 | Gln 47 | conflict |
| Thr 141 | Ala 141 | conflict |
| Ile 194 | Thr 194 | conflict |
| Ala 199 | Asp 199 | conflict |
| Val 209 | Ala 209 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Thr 182 | Met 468 | conflict |
| Lys 190 | Asn 476 | conflict |
| Tyr 209 | His 495 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Arg 56 | His 359 | conflict |
| Lys 73 | Val 376 | conflict |
| Val 75 | Ala 378 | conflict |
| Thr 134 | Lys 437 | conflict |
| Ala 219 | Thr 522 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 106095.6 | |
| All* | Total formula weight | 106095.6 |
