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8Y05

Crystal structure of LbCas12a in complex with crRNA and 9nt target DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
LbCas12apolymer1228143888.41UniProt (A0A5S8WF58)
Pfam (PF18501)
Pfam (PF21918)
Pfam (PF22222)
Pfam (PF18516)
Pfam (PF18510)
Lachnospiraceae bacterium ND2006
2B
(B)
RNA (29-MER)polymer4012804.71Lachnospiraceae bacterium ND2006
3C
(C)
DNA (5'-D(P*CP*TP*GP*GP*AP*TP*GP*CP*GP*TP*AP*AP*AP*GP*GP*AP*CP*G)-3')polymer185605.61Lachnospiraceae bacterium ND2006
4D
(D)
DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*TP*T)-3')polymer113290.21Lachnospiraceae bacterium ND2006
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6F
(A)
waterwater18.06Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight165588.8
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight165613.1
*Water molecules are not included.

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PDB entries from 2025-12-17

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