8XW7

Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Pyruvate kinase	polymer	521	56993.6	2	UniProt (Q8DQ84) In PDB	Streptococcus pneumoniae R6
2	A, B	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
4	A, B	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	2	Chemie (FBP)
5	A, B	OXALATE ION	non-polymer		88.0	2	Chemie (OXL)
6	A, B	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
7	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8		water	water		18.0	364	Chemie (HOH)

Sequence modifications

A, B: 1 - 501 (UniProt: Q8DQ84)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	113987.2
Non-Polymers*	Number of molecules	13
	Total formula weight	1978.2
All*	Total formula weight	115965.4

*Water molecules are not included.