8XV9
Fedratinib-bound human SLC19A3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Soluble cytochrome b562,Thiamine transporter 2 | polymer | 607 | 67910.0 | 1 | UniProt (P0ABE7) UniProt (Q9BZV2) Pfam (PF07361) Pfam (PF01770) In PDB | Escherichia coli | Cytochrome b-562,ThTr-2,ThTr2,Solute carrier family 19 member 3 |
2 | A | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide | non-polymer | 524.7 | 1 | Chemie (2TA) |
Sequence modifications
A: -95 - 10 (UniProt: P0ABE7)
A: 11 - 496 (UniProt: Q9BZV2)
PDB | External Database | Details |
---|---|---|
Leu -107 | - | expression tag |
Glu -106 | - | expression tag |
Val -105 | - | expression tag |
Leu -104 | - | expression tag |
Phe -103 | - | expression tag |
Gln -102 | - | expression tag |
Gly -101 | - | expression tag |
Pro -100 | - | expression tag |
Ser -99 | - | expression tag |
Arg -98 | - | expression tag |
Ala -97 | - | expression tag |
Thr -96 | - | expression tag |
Trp -89 | Met 29 | conflict |
Ile 6 | His 124 | conflict |
Leu 10 | Arg 128 | conflict |
PDB | External Database | Details |
---|---|---|
Ser 497 | - | expression tag |
Asn 498 | - | expression tag |
Ser 499 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 67910.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 524.7 | |
All* | Total formula weight | 68434.7 |