8XUT

XBB.1.5 Spike Trimer in complex with heparan sulfate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C	Spike glycoprotein	polymer	1269	141096.5	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	A, B, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	48	Chemie (NAG)
3	A	2-O-sulfo-beta-L-altropyranuronic acid	non-polymer		274.2	1	Chemie (IDU)

Sequence modifications

B, A, C: 4 - 1273 (UniProt: P0DTC2)

PDB	External Database	Details
Ile 22	Thr 19	variant
-	Leu 24	deletion
-	Pro 25	deletion
-	Pro 26	deletion
Ser 27	Ala 27	variant
Ala 83	Val 83	variant
Asp 142	Gly 142	variant
-	Tyr 144	deletion
Gln 146	His 146	variant
Glu 183	Gln 183	variant
Glu 213	Val 213	variant
Val 252	Gly 252	variant
His 339	Gly 339	variant
Thr 346	Arg 346	variant
Ile 368	Leu 368	variant
Phe 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Ala 376	Thr 376	variant
Asn 405	Asp 405	variant
Ser 408	Arg 408	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Pro 445	Val 445	variant
Ser 446	Gly 446	variant
Lys 460	Asn 460	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Pro 486	Phe 486	variant
Ser 490	Phe 490	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
Gly 614	Asp 614	variant
Tyr 655	His 655	variant
Lys 679	Asn 679	variant
His 681	Pro 681	variant
Lys 764	Asn 764	variant
Tyr 796	Asp 796	variant
His 954	Gln 954	variant
Lys 969	Asn 969	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	423289.5
Non-Polymers*	Number of molecules	49
	Total formula weight	10892.2
All*	Total formula weight	434181.7

*Water molecules are not included.