8XTX

Structure of human VAChT in an apo conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Vesicular acetylcholine transporter,Green fluorescent protein,antibody	polymer	851	91944.4	1	UniProt (Q16572) UniProt (P42212) Pfam (PF01353) Pfam (PF07690)	Homo sapiens (human)	VAChT,Solute carrier family 18 member 3

Sequence modifications

A: -227 - -202 (UniProt: Q16572)
A: -201 - 26 (UniProt: P42212)

PDB	External Database	Details
Arg -173	Ser 30	engineered mutation
Asn -164	Tyr 39	engineered mutation
Leu -139	Phe 64	engineered mutation
Thr -138	Ser 65	engineered mutation
Arg -123	Gln 80	engineered mutation
Ser -104	Phe 99	engineered mutation
Thr -98	Asn 105	engineered mutation
Phe -58	Tyr 145	engineered mutation
Thr -50	Met 153	engineered mutation
Ala -40	Val 163	engineered mutation
Val -32	Ile 171	engineered mutation
Val 3	Ala 206	engineered mutation

A: 27 - 476 (UniProt: Q16572)
A: 477 - 623 (PDB: 8XTX)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	91944.4
All*	Total formula weight	91944.4

*Water molecules are not included.