8XSD

BA.5 Spike complex with CR9

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1289	142974.4	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	D, F, H (H, G, I)	CR9 heavy chain	polymer	115	12320.9	3		Homo sapiens
3	E, G, I (L, J, K)	CR9 light chain	polymer	107	11595.8	3		Homo sapiens

Sequence modifications

A, B, C: 4 - 1211 (UniProt: P0DTC2)

PDB	External Database	Details
Ile 22	Thr 19	variant
-	Leu 24	deletion
-	Pro 25	deletion
-	Pro 26	deletion
Ser 27	Ala 27	variant
-	His 69	deletion
-	Val 70	deletion
Asp 140	Gly 142	variant
Gly 211	Val 213	variant
Asp 337	Gly 339	variant
Phe 369	Ser 371	variant
Pro 371	Ser 373	variant
Phe 373	Ser 375	variant
Ala 374	Thr 376	variant
Asn 403	Asp 405	variant
Ser 406	Arg 408	variant
Asn 415	Lys 417	variant
Lys 438	Asn 440	variant
Arg 450	Leu 452	variant
Asn 475	Ser 477	variant
Lys 476	Thr 478	variant
Ala 482	Glu 484	variant
Val 484	Phe 486	variant
Arg 496	Gln 498	variant
Tyr 499	Asn 501	variant
His 503	Tyr 505	variant
Gly 612	Asp 614	variant
Tyr 653	His 655	variant
Ser 656	Asn 658	variant
Lys 677	Asn 679	variant
His 679	Pro 681	variant
Ala 681	Arg 683	variant
Ala 683	Arg 685	variant
Lys 762	Asn 764	variant
Tyr 794	Asp 796	variant
Pro 815	Phe 817	variant
Pro 890	Ala 892	variant
Pro 897	Ala 899	variant
Pro 940	Ala 942	variant
His 952	Gln 954	variant
Lys 967	Asn 969	variant
Pro 984	Lys 986	variant
Pro 985	Val 987	variant
Gly 1212	-	expression tag
Gly 1213	-	expression tag
Ser 1214	-	expression tag
Gly 1215	-	expression tag
Gly 1216	-	expression tag
Ser 1217	-	expression tag
Tyr 1218	-	expression tag
Ile 1219	-	expression tag
Pro 1220	-	expression tag
Glu 1221	-	expression tag
Ala 1222	-	expression tag
Pro 1223	-	expression tag
Arg 1224	-	expression tag
Asp 1225	-	expression tag
Gly 1226	-	expression tag
Gln 1227	-	expression tag
Ala 1228	-	expression tag
Tyr 1229	-	expression tag
Val 1230	-	expression tag
Arg 1231	-	expression tag
Lys 1232	-	expression tag
Asp 1233	-	expression tag
Gly 1234	-	expression tag
Glu 1235	-	expression tag
Trp 1236	-	expression tag
Val 1237	-	expression tag
Leu 1238	-	expression tag
Leu 1239	-	expression tag
Ser 1240	-	expression tag
Thr 1241	-	expression tag
Phe 1242	-	expression tag
Leu 1243	-	expression tag
Gly 1244	-	expression tag
Arg 1245	-	expression tag
Ser 1246	-	expression tag
Leu 1247	-	expression tag
Glu 1248	-	expression tag
Val 1249	-	expression tag
Leu 1250	-	expression tag
Phe 1251	-	expression tag
Gln 1252	-	expression tag
Gly 1253	-	expression tag
Pro 1254	-	expression tag
Gly 1255	-	expression tag
Trp 1256	-	expression tag
Ser 1257	-	expression tag
His 1258	-	expression tag
Pro 1259	-	expression tag
Gln 1260	-	expression tag
Phe 1261	-	expression tag
Glu 1262	-	expression tag
Lys 1263	-	expression tag
Gly 1264	-	expression tag
Gly 1265	-	expression tag
Gly 1266	-	expression tag
Ser 1267	-	expression tag
Gly 1268	-	expression tag
Gly 1269	-	expression tag
Gly 1270	-	expression tag
Ser 1271	-	expression tag
Gly 1272	-	expression tag
Gly 1273	-	expression tag
Ser 1274	-	expression tag
Ser 1275	-	expression tag
Ala 1276	-	expression tag
Trp 1277	-	expression tag
Ser 1278	-	expression tag
His 1279	-	expression tag
Pro 1280	-	expression tag
Gln 1281	-	expression tag
Phe 1282	-	expression tag
Glu 1283	-	expression tag
Lys 1284	-	expression tag
His 1285	-	expression tag
His 1286	-	expression tag
His 1287	-	expression tag
His 1288	-	expression tag
His 1289	-	expression tag
His 1290	-	expression tag
His 1291	-	expression tag
His 1292	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	500673.1
All*	Total formula weight	500673.1

*Water molecules are not included.