8XS9
Crystal structure of the DNA-bound AHR-ARNT heterodimer in complex with beta-Naphthoflavone
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aryl hydrocarbon receptor nuclear translocator | polymer | 382 | 43231.1 | 1 | UniProt (P27540) Pfam (PF00010) Pfam (PF00989) Pfam (PF14598) | Homo sapiens (human) | ARNT protein |
| 2 | B (B) | Aryl hydrocarbon receptor | polymer | 395 | 45242.7 | 1 | UniProt (I3LF82) Pfam (PF00010) Pfam (PF00989) Pfam (PF08447) | Sus scrofa (pig) | |
| 3 | C (C) | DNAF | polymer | 21 | 6473.2 | 1 | Homo sapiens | ||
| 4 | D (D) | DNAR | polymer | 21 | 6415.1 | 1 | Homo sapiens | ||
| 5 | E (A) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 6 | F (B) | (3R)-3-phenyl-2,3-dihydrobenzo[f]chromen-1-one | non-polymer | 274.3 | 1 | Chemie (A1LWJ) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 85 - 465 (UniProt: P27540)
B: 26 - 413 (UniProt: I3LF82)
| PDB | External Database | Details |
|---|---|---|
| Met 84 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
| His 414 | - | expression tag |
| His 415 | - | expression tag |
| His 416 | - | expression tag |
| His 417 | - | expression tag |
| His 418 | - | expression tag |
| His 419 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 101362.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 428.6 | |
| All* | Total formula weight | 101790.7 |
