8XPX
The Crystal Structure of PARP12 from Biortus.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein mono-ADP-ribosyltransferase PARP12 | polymer | 196 | 22397.0 | 2 | UniProt (Q9H0J9) Pfam (PF00644) | Homo sapiens (human) | ADP-ribosyltransferase diphtheria toxin-like 12,ARTD12,Poly [ADP-ribose] polymerase 12,PARP-12,Zinc finger CCCH domain-containing protein 1 |
| 2 | C, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D, J (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | E, F, G, I, K... (A, B) | ACETATE ION | non-polymer | 59.0 | 7 | Chemie (ACT) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A, B: 489 - 684 (UniProt: Q9H0J9)
| PDB | External Database | Details |
|---|---|---|
| Val 570 | Phe 570 | conflict |
| Gly 573 | Ala 573 | conflict |
| His 577 | Gln 577 | conflict |
| Phe 607 | Tyr 607 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44793.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 749.7 | |
| All* | Total formula weight | 45543.6 |
