8XPP
Crystal structure of the enterovirus 71 RdRP elongation complex with the nucleoside monophosphate form of compound HNC-1664 at product position -1 (post-translocation state)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 468 | 53408.5 | 1 | UniProt (E5RPG3) Pfam (PF00680) UniProt (by SIFTS) (B6F2F5) | Enterovirus A71 | |
| 2 | B (B) | RNA (35-MER) | polymer | 35 | 11370.9 | 1 | synthetic construct | ||
| 3 | C (C) | RNA (17-MER) | polymer | 17 | 5467.1 | 1 | synthetic construct | ||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 1 - 462 (UniProt: E5RPG3)
| PDB | External Database | Details |
|---|---|---|
| Met 291 | Cys 2022 | engineered mutation |
| His 463 | - | expression tag |
| His 464 | - | expression tag |
| His 465 | - | expression tag |
| His 466 | - | expression tag |
| His 467 | - | expression tag |
| His 468 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 70246.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 70311.8 |
