8XOJ
Cryo-EM structure of GPR30-Gq complex structure in the presence of G-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha-q | polymer | 361 | 41632.2 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P63092) UniProt (by SIFTS) (P63096) | Homo sapiens | |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 351 | 38744.4 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens | Transducin beta chain 1 |
| 3 | C (E) | scFv16 | polymer | 247 | 26293.3 | 1 | synthetic construct | ||
| 4 | D (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens | G gamma-I |
| 5 | E (R) | G-protein coupled estrogen receptor 1 | polymer | 375 | 42291.5 | 1 | UniProt (Q99527) Pfam (PF00001) | Homo sapiens | Chemoattractant receptor-like 2,Flow-induced endothelial G-protein coupled receptor 1,FEG-1,G protein-coupled estrogen receptor 1,G-protein coupled receptor 30,GPCR-Br,IL8-related receptor DRY12,Lymphocyte-derived G-protein coupled receptor,LYGPR,Membrane estrogen receptor,mER |
Sequence modifications
B: 2 - 340 (UniProt: P62873)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 156822.5 | |
| All* | Total formula weight | 156822.5 |
