8XMJ
Cryo-EM structure of human ZnT1 WT, in the presence of zinc, determined in heterogeneous conformations- one subunit in an inward-facing and the other in an outward-facing conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Proton-coupled zinc antiporter SLC30A1 | polymer | 530 | 58055.6 | 2 | UniProt (Q9Y6M5) Pfam (PF01545) | Homo sapiens (human) | Solute carrier family 30 member 1,Zinc transporter 1 |
| 2 | C, D, E, F, H... (B, A) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | G, I (B, A) | Lauryl Maltose Neopentyl Glycol | non-polymer | 1005.2 | 2 | Chemie (AV0) | |||
| 4 | M (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) |
Sequence modifications
B, A: 1 - 507 (UniProt: Q9Y6M5)
| PDB | External Database | Details |
|---|---|---|
| Ser 508 | - | expression tag |
| Arg 509 | - | expression tag |
| Leu 510 | - | expression tag |
| Glu 511 | - | expression tag |
| Glu 512 | - | expression tag |
| Glu 513 | - | expression tag |
| Leu 514 | - | expression tag |
| Arg 515 | - | expression tag |
| Arg 516 | - | expression tag |
| Arg 517 | - | expression tag |
| Thr 518 | - | expression tag |
| Glu 519 | - | expression tag |
| Gly 520 | - | expression tag |
| Gly 521 | - | expression tag |
| Ser 522 | - | expression tag |
| Ser 523 | - | expression tag |
| Asp 524 | - | expression tag |
| Leu 525 | - | expression tag |
| Glu 526 | - | expression tag |
| Val 527 | - | expression tag |
| Leu 528 | - | expression tag |
| Phe 529 | - | expression tag |
| Gln 530 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116111.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3020.4 | |
| All* | Total formula weight | 119131.5 |
