8XM7
Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Engulfment and cell motility protein 1 | polymer | 733 | 84337.7 | 1 | UniProt (Q92556) Pfam (PF11841) Pfam (PF04727) Pfam (PF16457) | Homo sapiens (human) | Protein ced-12 homolog |
| 2 | B (B) | Dedicator of cytokinesis protein 5 | polymer | 1648 | 191492.1 | 1 | UniProt (Q9H7D0) Pfam (PF00018) Pfam (PF16172) Pfam (PF14429) Pfam (PF06920) Pfam (PF20422) Pfam (PF20421) | Homo sapiens (human) | |
| 3 | C (D) | Rho-related GTP-binding protein RhoG | polymer | 203 | 22362.4 | 1 | UniProt (P84095) Pfam (PF00071) | Homo sapiens (human) | |
| 4 | D (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (D) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) |
Sequence modifications
A: 1 - 727 (UniProt: Q92556)
B: 1 - 1642 (UniProt: Q9H7D0)
D: 1 - 184 (UniProt: P84095)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Arg 1285 | Lys 1285 | variant |
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Leu 61 | Gln 61 | engineered mutation |
| Ser 185 | - | expression tag |
| Gly 186 | - | expression tag |
| Pro 187 | - | expression tag |
| Ser 188 | - | expression tag |
| Ser 189 | - | expression tag |
| Gly 190 | - | expression tag |
| Glu 191 | - | expression tag |
| Asn 192 | - | expression tag |
| Leu 193 | - | expression tag |
| Tyr 194 | - | expression tag |
| Phe 195 | - | expression tag |
| Gln 196 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 298192.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 298739.7 |
