8XLR

Cryo-EM structure of Ca2+-bound TMEM16A in complex with Tamsulosin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Anoctamin-1	polymer	960	111059.0	2	UniProt (Q8BHY3) Pfam (PF16178) Pfam (PF04547)	Mus musculus (house mouse)	Transmembrane protein 16A
2	C, D, E, F, KA... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
3	AA, AB, BA, BB, CA... (A, B)	TETRADECANE	non-polymer		198.4	50	Chemie (C14)
4	EA, FA, NB, OB (A, B)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
5	GA, PB (A, B)	Tamsulosin	non-polymer		408.5	2	Chemie (JGX)
6	HA, JA (A, B)	HEXANE	non-polymer		86.2	2	Chemie (HEX)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	222118.0
Non-Polymers*	Number of molecules	66
	Total formula weight	12838.8
All*	Total formula weight	234956.7

*Water molecules are not included.