8XLK
Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 938 | 105645.9 | 2 | UniProt (P35439) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B (B) | Glutamate receptor ionotropic, NMDA 2A | polymer | 1464 | 165667.0 | 1 | UniProt (Q00959) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF10565) | Rattus norvegicus (Norway rat) | GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,N-methyl D-aspartate receptor subtype 2A,NMDAR2A,NR2A |
| 3 | D (D) | Glutamate receptor ionotropic, NMDA 2B | polymer | 1482 | 166274.2 | 1 | UniProt (Q00960) Pfam (PF00060) Pfam (PF10565) Pfam (PF01094) Pfam (PF10613) | Rattus norvegicus (Norway rat) | GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NMDAR2B,NR2B |
| 4 | E, I (E, I) | Heavy Chain of GluN1 Fab, 4F11 | polymer | 140 | 15536.4 | 2 | Mus musculoides | ||
| 5 | F, J (F, J) | Light Chain of GluN1 Fab, 4F11 | polymer | 131 | 13916.6 | 2 | Mus musculoides | ||
| 6 | G (G) | Heavy Chain of GluN2A Fab, 28C | polymer | 227 | 24055.0 | 1 | Mus musculoides | ||
| 7 | H (H) | Light Chain of GluN2A Fab, 28C | polymer | 212 | 22412.9 | 1 | Mus musculoides | ||
| 8 | K (K) | Heavy Chain of GluN2B Fab2 | polymer | 248 | 26660.0 | 1 | Mus musculoides | ||
| 9 | L (L) | Light Chain of GluN2B Fab2 | polymer | 265 | 28581.8 | 1 | Mus musculoides | ||
| 10 | M, O (M, O) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G62182OO) | |||
| 11 | N (N) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 12 | AA, BA, CA, DA, EA... (C, D, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 20 | Chemie (NAG) | |||
| 13 | KA, Z (D, B) | (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid | non-polymer | 252.2 | 2 | Chemie (7RC) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 703848.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1597.5 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 4928.6 | |
| All* | Total formula weight | 710374.5 |
