8XKM

Cryo-EM structure of human insulin receptor bound to 4 IGF-I, conformation 3

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Isoform Short of Insulin receptor	polymer	1370	155329.1	2	UniProt (P06213) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF17870) Pfam (PF07714)	Homo sapiens (human)
2	C, D, E, F (C, E, F, D)	Insulin-like growth factor I	polymer	195	21881.3	4	UniProt (P05019) Pfam (PF00049)	Homo sapiens (human)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	398183.5
All*	Total formula weight	398183.5

*Water molecules are not included.