8XI6
SARS-CoV-2 Omicron BQ.1.1 Variant Spike Protein Complexed with MO11 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1247 | 138784.1 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | D, F, H | MO11 heavy chain | polymer | 232 | 24479.3 | 3 | Homo sapiens | ||
3 | E, G, I | MO11 light chain | polymer | 214 | 22848.3 | 3 | Homo sapiens | ||
4 | J, K, L, O, P... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
5 | M, R, W | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB GlyTouCan (G32152BH) | |||
6 | N, S, X | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
7 | A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
A, B, C: 4 - 1213 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Ile 22 | Thr 19 | variant |
- | Leu 24 | deletion |
- | Pro 25 | deletion |
- | Pro 26 | deletion |
Ser 27 | Ala 27 | variant |
- | His 69 | deletion |
- | Val 70 | deletion |
Asp 142 | Gly 142 | variant |
Gly 213 | Val 213 | variant |
Asp 339 | Gly 339 | variant |
Thr 346 | Arg 346 | variant |
Phe 371 | Ser 371 | variant |
Pro 373 | Ser 373 | variant |
Phe 375 | Ser 375 | variant |
Ala 376 | Thr 376 | variant |
Asn 405 | Asp 405 | variant |
Ser 408 | Arg 408 | variant |
Asn 417 | Lys 417 | variant |
Lys 440 | Asn 440 | variant |
Thr 444 | Lys 444 | variant |
Arg 452 | Leu 452 | variant |
Lys 460 | Asn 460 | variant |
Asn 477 | Ser 477 | variant |
Lys 478 | Thr 478 | variant |
Ala 484 | Glu 484 | variant |
Val 486 | Phe 486 | variant |
Arg 498 | Gln 498 | variant |
Tyr 501 | Asn 501 | variant |
His 505 | Tyr 505 | variant |
Gly 614 | Asp 614 | variant |
Tyr 655 | His 655 | variant |
Lys 682 | Asn 679 | variant |
His 684 | Pro 681 | variant |
- | Arg 682 | deletion |
- | Arg 683 | deletion |
- | Arg 685 | deletion |
Lys 764 | Asn 764 | variant |
Tyr 796 | Asp 796 | variant |
Pro 817 | Phe 817 | engineered mutation |
Pro 892 | Ala 892 | engineered mutation |
Pro 899 | Ala 899 | engineered mutation |
Pro 942 | Ala 942 | engineered mutation |
His 954 | Gln 954 | variant |
Lys 969 | Asn 969 | variant |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Leu 1214 | - | expression tag |
Glu 1215 | - | expression tag |
Val 1216 | - | expression tag |
Leu 1217 | - | expression tag |
Phe 1218 | - | expression tag |
Gln 1219 | - | expression tag |
Gly 1220 | - | expression tag |
Pro 1221 | - | expression tag |
Gly 1222 | - | expression tag |
Tyr 1223 | - | expression tag |
Ile 1224 | - | expression tag |
Pro 1225 | - | expression tag |
Glu 1226 | - | expression tag |
Ala 1227 | - | expression tag |
Pro 1228 | - | expression tag |
Arg 1229 | - | expression tag |
Asp 1230 | - | expression tag |
Gly 1231 | - | expression tag |
Gln 1232 | - | expression tag |
Ala 1233 | - | expression tag |
Tyr 1234 | - | expression tag |
Val 1235 | - | expression tag |
Arg 1236 | - | expression tag |
Lys 1237 | - | expression tag |
Asp 1238 | - | expression tag |
Gly 1239 | - | expression tag |
Glu 1240 | - | expression tag |
Trp 1241 | - | expression tag |
Val 1242 | - | expression tag |
Phe 1243 | - | expression tag |
Leu 1244 | - | expression tag |
Ser 1245 | - | expression tag |
Thr 1246 | - | expression tag |
Phe 1247 | - | expression tag |
Leu 1248 | - | expression tag |
Gly 1249 | - | expression tag |
His 1250 | - | expression tag |
His 1251 | - | expression tag |
His 1252 | - | expression tag |
His 1253 | - | expression tag |
His 1254 | - | expression tag |
His 1255 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 558335.3 | |
Branched | Number of molecules | 15 |
Total formula weight | 7729.3 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 4645.4 | |
All* | Total formula weight | 570710.0 |