8XGM
Cryo-EM structure of human GPR1 bound to chemerin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (S) | scFV16 | polymer | 247 | 26337.3 | 1 | Vicugna pacos | ||
| 2 | B (A) | G-protein coupled receptor 1 | polymer | 306 | 35785.3 | 1 | UniProt (P46091) Pfam (PF00001) | Homo sapiens (human) | Chemerin-like receptor 2 |
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1,G protein beta subunit |
| 4 | D (C) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40445.1 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | |
| 5 | E (G) | Guanine nucleotide-binding protein subunit gamma | polymer | 55 | 6089.0 | 1 | UniProt (A0A6P5CFI6) Pfam (PF00631) UniProt (by SIFTS) (P59768) | Homo sapiens (human) | |
| 6 | F (D) | Retinoic acid receptor responder protein 2 | polymer | 137 | 15904.2 | 1 | UniProt (Q99969) | Homo sapiens (human) | Chemerin |
| 7 | G (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) |
Sequence modifications
S: 1 - 136 (PDB: 8XGM)
S: 137 - 247 (PDB: 8XGM)
C: 1 - 354 (UniProt: P63096)
S: 137 - 247 (PDB: 8XGM)
C: 1 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Gly 203 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 161977.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 386.7 | |
| All* | Total formula weight | 162364.4 |
