8XGM
Cryo-EM structure of human GPR1 bound to chemerin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (S) | scFV16 | polymer | 247 | 26337.3 | 1 | Vicugna pacos | ||
| 2 | B (A) | G-protein coupled receptor 1 | polymer | 306 | 35785.3 | 1 | UniProt (P46091) Pfam (PF00001) | Homo sapiens (human) | Chemerin-like receptor 2 |
| 3 | C (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (human) | Transducin beta chain 1,G protein beta subunit |
| 4 | D (C) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40445.1 | 1 | UniProt (P63096) Pfam (PF00503) | Homo sapiens (human) | |
| 5 | E (G) | Guanine nucleotide-binding protein subunit gamma | polymer | 55 | 6089.0 | 1 | UniProt (A0A6P5CFI6) Pfam (PF00631) UniProt (by SIFTS) (P59768) | Homo sapiens (human) | |
| 6 | F (D) | Retinoic acid receptor responder protein 2 | polymer | 137 | 15904.2 | 1 | UniProt (Q99969) | Homo sapiens (human) | Chemerin |
| 7 | G (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (45044259) PubChem (49853509) PubChem (50990013) PubChem (176980071) PubChem (18640088) PubChem (52934537) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (44654663) PubChem (46937002) PubChem (56621683) PubChem (59274407) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (1551269) PubChem (90070115) PubChem (59450329) PubChem (59628412) PubChem (117965027) PubChem (6432564) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (132837164) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (304) PubChem (138967089) PubChem (139566851) PubChem (89951918) PubChem (90224410) PubChem (15939944) PubChem (91298236) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (638019) PubChem (101624109) PubChem (1549081) PubChem (1553803) PubChem (171828367) PubChem (173516975) PubChem (124225449) PubChem (124429284) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (6419195) PubChem (6994560) PubChem (130459183) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (131992107) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (139568882) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) |
Sequence modifications
S: 1 - 136 (PDB: 8XGM)
S: 137 - 247 (PDB: 8XGM)
C: 1 - 354 (UniProt: P63096)
S: 137 - 247 (PDB: 8XGM)
C: 1 - 354 (UniProt: P63096)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Gly 203 | engineered mutation |
| Ser 326 | Ala 326 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 161977.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 386.7 | |
| All* | Total formula weight | 162364.4 |
