8XFP
the pentamerA complex of LGR4-RSPO2-ZNRF3(delta RING)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leucine-rich repeat-containing G-protein coupled receptor 4 | polymer | 951 | 104565.7 | 1 | UniProt (Q9BXB1) Pfam (PF01462) Pfam (PF13855) Pfam (PF00001) | Homo sapiens (human) | G-protein coupled receptor 48 |
| 2 | B (E) | nanobody Nb52 | polymer | 560 | 59692.8 | 1 | Camelus bactrianus | ||
| 3 | C, E (C, H) | E3 ubiquitin-protein ligase ZNRF3 | polymer | 936 | 100703.9 | 2 | UniProt (Q9ULT6) Pfam (PF17123) Pfam (PF18212) | Homo sapiens (human) | RING finger protein 203,RING-type E3 ubiquitin transferase ZNRF3,Zinc/RING finger protein 3 |
| 4 | D, F (G, J) | R-spondin-2 | polymer | 101 | 11631.4 | 2 | UniProt (Q8BFU0) Pfam (PF15913) UniProt (by SIFTS) (Q6UXX9) | Homo sapiens (human) | Cysteine-rich and single thrombospondin domain-containing protein 2,Cristin-2,mCristin-2,Roof plate-specific spondin-2 |
Sequence modifications
G, J: 41 - 141 (UniProt: Q8BFU0)
| PDB | External Database | Details |
|---|---|---|
| Ala 130 | Asp 130 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 388929.1 | |
| All* | Total formula weight | 388929.1 |
