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8XB1

Crystal structure of FLT3 in complex with a Pyrazinamide Macrocycle derivative

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Receptor-type tyrosine-protein kinase FLT3polymer34639927.51Pfam (PF07714)
UniProt (by SIFTS) (P36888)
Homo sapiens
2B
(A)
3^3-ethyl-5^4-morpholino-6,9-dioxa-2,4-diaza-3(2,6)-pyrazina-1(4,1)-piperidina-5(1,3)-benzenacycloundecaphane-3^5-carboxamidenon-polymer511.61Chemie (ZX3)
PubChem (171713848)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39927.5
Non-Polymers*Number of molecules1
Total formula weight511.6
All*Total formula weight40439.1
*Water molecules are not included.

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PDB entries from 2026-03-25

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