8XAM
Co-crystal structure of compound 7 in complex with MAT2A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | S-adenosylmethionine synthase isoform type-2 | polymer | 380 | 42001.8 | 2 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB | Homo sapiens (human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
| 2 | A, B | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 3 | B | 2-[3-[7-chloranyl-4-(dimethylamino)-2-oxidanylidene-quinazolin-1-yl]phenoxy]-~{N}-[3-[7-chloranyl-4-(dimethylamino)-2-oxidanylidene-quinazolin-1-yl]phenyl]ethanamide | non-polymer | 670.5 | 1 | Chemie (XRH) | |||
| 4 | water | water | 18.0 | 1098 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84003.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1467.4 | |
| All* | Total formula weight | 85471.0 |
