8X9T
Identification, structure and agonist design of an androgen membrane receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gs protein alpha subunit | polymer | 361 | 41879.5 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P04896) | Bos taurus | |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 344 | 37784.3 | 1 | UniProt (P54311) Pfam (PF00400) | Rattus norvegicus (Norway rat) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P63212) Pfam (PF00631) | Bos taurus (domestic cattle) | G gamma-I |
| 4 | D (R) | Adhesion G-protein coupled receptor D1 | polymer | 598 | 65688.8 | 1 | UniProt (Q6QNK2) Pfam (PF01825) Pfam (PF00002) | Homo sapiens (human) | |
| 5 | E (S) | scFv16 | polymer | 267 | 28782.0 | 1 | synthetic construct | ||
| 6 | F (R) | methyl 3-[2-(2,4-dimethylphenoxy)ethanoylamino]-4-(4-ethylpiperazin-1-yl)benzoate | non-polymer | 425.5 | 1 | Chemie (YNH) |
Sequence modifications
B: 2 - 340 (UniProt: P54311)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Gln 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181995.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 425.5 | |
| All* | Total formula weight | 182421.2 |
