8X8Z
Crystal structure of ROCK2 with GNS-2664 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Rho-associated protein kinase 2 | polymer | 391 | 45028.2 | 2 | UniProt (O75116) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | C, F (A, B) | ~{N}-methyl-3-[[6-(3-methyl-1,2-oxazol-4-yl)-1-oxidanylidene-isoquinolin-2-yl]methyl]benzamide | non-polymer | 373.4 | 2 | Chemie (YEI) | |||
| 3 | D, E, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90056.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1035.0 | |
| All* | Total formula weight | 91091.5 |
