8X7L
EB-bound E46K alpha-synuclein fibrils
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, C, D, E, F...) | Alpha-synuclein | polymer | 140 | 14476.2 | 10 | UniProt (P37840) Pfam (PF01387) | Homo sapiens (human) | |
| 2 | K, L, M, N, O... (F, H, I) | 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid | non-polymer | 872.9 | 6 | Chemie (IZ8) |
Sequence modifications
A, C, D, E, F, G, H, I, J, B: 1 - 140 (UniProt: P37840)
| PDB | External Database | Details |
|---|---|---|
| Lys 46 | Glu 46 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 144761.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 5237.3 | |
| All* | Total formula weight | 149999.0 |
