8X7B
ThT-bound E46K alpha-synuclein fibrils
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Alpha-synuclein | polymer | 140 | 14476.2 | 10 | UniProt (P37840) Pfam (PF01387) | Homo sapiens (human) | |
| 2 | K, L, M, N, O... (A, C, E, F, I...) | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium | non-polymer | 283.4 | 12 | Chemie (TFX) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 140 (UniProt: P37840)
| PDB | External Database | Details |
|---|---|---|
| Lys 46 | Glu 46 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 144761.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3400.9 | |
| All* | Total formula weight | 148162.7 |
