8X4O
Crystal structure of the Y135A mutant of DIMT1 in complex with 5'-methylthioadenosine from Pyrococcus horikoshii
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Probable ribosomal RNA small subunit methyltransferase A | polymer | 290 | 33273.0 | 2 | UniProt (O59487) In PDB | Pyrococcus horikoshii OT3 | |
2 | A, B | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 2 | Chemie (MTA) | |||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
5 | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A, B: 23 - 290 (UniProt: O59487)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ser 2 | - | expression tag |
Ser 3 | - | expression tag |
Arg 4 | - | expression tag |
Ile 5 | - | expression tag |
Arg 6 | - | expression tag |
Ile 7 | - | expression tag |
Asn 8 | - | expression tag |
Thr 9 | - | expression tag |
Lys 10 | - | expression tag |
Ser 11 | - | expression tag |
Leu 12 | - | expression tag |
Leu 13 | - | expression tag |
Val 14 | - | expression tag |
Gln 15 | - | expression tag |
Pro 16 | - | expression tag |
Gly 17 | - | expression tag |
Tyr 18 | - | expression tag |
Ser 19 | - | expression tag |
Gly 20 | - | expression tag |
Ser 21 | - | expression tag |
Lys 22 | - | expression tag |
Ala 135 | Tyr 113 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 66546.0 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 849.6 | |
All* | Total formula weight | 67395.7 |