8X4I
Crystal structure of the D117A mutant of DIMT1 in complex with 5'-methylthioadenosine from Pyrococcus horikoshii
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Probable ribosomal RNA small subunit methyltransferase A | polymer | 290 | 33321.1 | 1 | UniProt (O59487) | Pyrococcus horikoshii OT3 | |
| 2 | B (A) | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 1 | Chemie (MTA) PubChem (149) PubChem (439176) PubChem (688097) PubChem (6541356) PubChem (13101165) PubChem (13101166) PubChem (25322898) PubChem (40467850) PubChem (44264468) PubChem (46874793) PubChem (51397472) PubChem (99302) PubChem (51397471) PubChem (453683) PubChem (98100246) PubChem (57104771) PubChem (58108938) PubChem (58682801) PubChem (59099797) PubChem (91614589) PubChem (124300729) PubChem (124300795) PubChem (134694842) PubChem (138107656) PubChem (164077596) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A: 23 - 290 (UniProt: O59487)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ser 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Arg 4 | - | expression tag |
| Ile 5 | - | expression tag |
| Arg 6 | - | expression tag |
| Ile 7 | - | expression tag |
| Asn 8 | - | expression tag |
| Thr 9 | - | expression tag |
| Lys 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Leu 12 | - | expression tag |
| Leu 13 | - | expression tag |
| Val 14 | - | expression tag |
| Gln 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Tyr 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| Lys 22 | - | expression tag |
| Ala 117 | Asp 95 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33321.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 362.7 | |
| All* | Total formula weight | 33683.9 |
