8X47

Crystal structure of DIMT1 in complex with S-adenosyl-L-homocysteine (SAH) from Pyrococcus horikoshii

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Probable ribosomal RNA small subunit methyltransferase A	polymer	290	33365.1	1	UniProt (O59487) Pfam (PF00398)	Pyrococcus horikoshii OT3
2	B (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
3	C, D (A)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E (A)	SULFITE ION	non-polymer		80.1	1	Chemie (SO3)
5	F (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	G (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	H (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
8	I (A)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
9	J (A)	ARGININE	non-polymer		175.2	1	Chemie (ARG)
10	K (A)	water	water		18.0	35	Chemie (HOH)

Sequence modifications

A: 23 - 290 (UniProt: O59487)

PDB	External Database	Details
Met 1	-	initiating methionine
Ser 2	-	expression tag
Ser 3	-	expression tag
Arg 4	-	expression tag
Ile 5	-	expression tag
Arg 6	-	expression tag
Ile 7	-	expression tag
Asn 8	-	expression tag
Thr 9	-	expression tag
Lys 10	-	expression tag
Ser 11	-	expression tag
Leu 12	-	expression tag
Leu 13	-	expression tag
Val 14	-	expression tag
Gln 15	-	expression tag
Pro 16	-	expression tag
Gly 17	-	expression tag
Tyr 18	-	expression tag
Ser 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Lys 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33365.1
Non-Polymers*	Number of molecules	9
	Total formula weight	1181.0
All*	Total formula weight	34546.1

*Water molecules are not included.