8X44

Crystal structure of DIMT1 in complex with 5'-methylthioadenosine from Pyrococcus horikoshii (FormI)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable ribosomal RNA small subunit methyltransferase A	polymer	290	33365.1	2	UniProt (O59487) Pfam (PF00398)	Pyrococcus horikoshii OT3
2	C, N (A, B)	5'-DEOXY-5'-METHYLTHIOADENOSINE	non-polymer		297.3	2	Chemie (MTA)
3	D, E, F, G, H... (A, B)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
4	J, K, R, S (A, B)	SULFITE ION	non-polymer		80.1	4	Chemie (SO3)
5	L, M, V, W (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
6	Q (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	T (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	U (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
9	X, Y (A, B)	water	water		18.0	197	Chemie (HOH)

Sequence modifications

A, B: 23 - 290 (UniProt: O59487)

PDB	External Database	Details
Met 1	-	initiating methionine
Ser 2	-	expression tag
Ser 3	-	expression tag
Arg 4	-	expression tag
Ile 5	-	expression tag
Arg 6	-	expression tag
Ile 7	-	expression tag
Asn 8	-	expression tag
Thr 9	-	expression tag
Lys 10	-	expression tag
Ser 11	-	expression tag
Leu 12	-	expression tag
Leu 13	-	expression tag
Val 14	-	expression tag
Gln 15	-	expression tag
Pro 16	-	expression tag
Gly 17	-	expression tag
Tyr 18	-	expression tag
Ser 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Lys 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66730.2
Non-Polymers*	Number of molecules	21
	Total formula weight	2052.3
All*	Total formula weight	68782.5

*Water molecules are not included.