8X2D
Crystal structure of H5 hemagglutinin from swan-infecting H5N8 influenza virus complexed with avian receptor analog LSTc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Hemagglutinin | polymer | 506 | 57704.0 | 3 | UniProt (A0A8E4ZAK5) Pfam (PF00509) | Influenza A virus | |
| 2 | D (D) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose | branched | 836.7 | 1 | In PDB GlyTouCan (G03509EL) | |||
| 3 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | G, H (G, H) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 2 | In PDB BIRD (PRD_900046) GlyTouCan (G73578JC) | |||
| 5 | I, J, K, L, M... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | O, P, Q (A, B, C) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 506 (UniProt: A0A8E4ZAK5)
| PDB | External Database | Details |
|---|---|---|
| Val 86 | Ala 102 | engineered mutation |
| Ile 188 | Thr 204 | engineered mutation |
| Asn 273 | His 289 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 173112.0 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3034.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 177474.0 |
