8X1X
SARS-CoV-2 Papain like protease (PLpro) in complex with inhibitor Lithocholic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Papain-like protease nsp3 | polymer | 316 | 35786.6 | 1 | UniProt (P0DTD1) Pfam (PF08715) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO |
| 2 | B, C, D (A) | (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid | non-polymer | 376.6 | 3 | Chemie (4OA) | |||
| 3 | E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | I (A) | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A: 1 - 315 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 111 | Cys 1674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35786.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1429.0 | |
| All* | Total formula weight | 37215.6 |
