8WZ7

The crystal structure of Legionella pneumophila adenosylhomocysteinase Lpg2021(I255A,T287A) in ternary complex with NAD and adenosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adenosylhomocysteinase	polymer	437	48300.0	1	UniProt (A0A2S6F4T2) Pfam (PF05221) Pfam (PF00670) UniProt (by SIFTS) (Q5ZTY7)	Legionella pneumophila
2	B (A)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
3	C (A)	ADENOSINE	non-polymer		267.2	1	Chemie (ADN)
4	D (A)	water	water		18.0	309	Chemie (HOH)

Sequence modifications

A: 15 - 441 (UniProt: A0A2S6F4T2)

PDB	External Database	Details
Met 5	-	initiating methionine
Gly 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
Ala 255	Ile 255	engineered mutation
Ala 287	Thr 287	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	48300.0
Non-Polymers*	Number of molecules	2
	Total formula weight	930.7
All*	Total formula weight	49230.6

*Water molecules are not included.