8WYT

Partially closed Falcilysin bound to MK-4815, from MK-4815-treated dataset

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Falcilysin	polymer	1158	135039.4	1	UniProt (Q76NL8) Pfam (PF00675) Pfam (PF05193) Pfam (PF08367) Pfam (PF22516)	Plasmodium falciparum 3D7
2	B (A)	2-(aminomethyl)-3,5-ditert-butyl-phenol	non-polymer		235.4	1	Chemie (H8F)
3	C (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A: 59 - 1193 (UniProt: Q76NL8)

PDB	External Database	Details
Met 36	-	initiating methionine
His 37	-	expression tag
His 38	-	expression tag
His 39	-	expression tag
His 40	-	expression tag
His 41	-	expression tag
His 42	-	expression tag
Ser 43	-	expression tag
Ser 44	-	expression tag
Gly 45	-	expression tag
Val 46	-	expression tag
Asp 47	-	expression tag
Leu 48	-	expression tag
Gly 49	-	expression tag
Thr 50	-	expression tag
Glu 51	-	expression tag
Asn 52	-	expression tag
Leu 53	-	expression tag
Tyr 54	-	expression tag
Phe 55	-	expression tag
Gln 56	-	expression tag
Ser 57	-	expression tag
Met 58	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	135039.4
Non-Polymers*	Number of molecules	2
	Total formula weight	300.8
All*	Total formula weight	135340.1

*Water molecules are not included.