8WYJ
The global map of Omicron Subvariants Spike with two antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1123 | 124552.3 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | D, H, L (E, I, S) | S309-HC | polymer | 127 | 14005.5 | 3 | Homo sapiens | ||
| 3 | E, I, M (G, K, T) | S309-KC | polymer | 106 | 11315.6 | 3 | Homo sapiens | ||
| 4 | F, J, N (H, D, Q) | SA55-HC | polymer | 125 | 13412.0 | 3 | Homo sapiens | ||
| 5 | G, K, O (F, J, R) | SA55_KC | polymer | 108 | 11880.1 | 3 | Homo sapiens | ||
| 6 | P, S, V (M, O, V) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 3 | In PDB GlyTouCan (G82348BZ) | |||
| 7 | Q, R, T, U, W... (L, N, P, U, W...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A, B, C: 20 - 1147 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ile 22 | Thr 19 | conflict |
| Thr 24 | Arg 21 | conflict |
| - | Leu 24 | deletion |
| - | Pro 25 | deletion |
| - | Pro 26 | deletion |
| Ser 27 | Ala 27 | conflict |
| Leu 50 | Ser 50 | conflict |
| - | His 69 | deletion |
| - | Val 70 | deletion |
| Phe 127 | Val 127 | conflict |
| Asp 142 | Gly 142 | conflict |
| - | Tyr 144 | deletion |
| Ser 157 | Phe 157 | conflict |
| Gly 158 | Arg 158 | conflict |
| - | Asn 211 | deletion |
| Ile 211 | Leu 212 | conflict |
| Gly 212 | Val 213 | conflict |
| Phe 215 | Leu 216 | conflict |
| Asn 245 | His 245 | conflict |
| Asp 264 | Ala 264 | conflict |
| Val 332 | Ile 332 | conflict |
| His 339 | Gly 339 | conflict |
| Thr 356 | Lys 356 | conflict |
| Phe 371 | Ser 371 | conflict |
| Pro 373 | Ser 373 | conflict |
| Phe 375 | Ser 375 | conflict |
| Ala 376 | Thr 376 | conflict |
| Lys 403 | Arg 403 | conflict |
| Asn 405 | Asp 405 | conflict |
| Ser 408 | Arg 408 | conflict |
| Asn 417 | Lys 417 | conflict |
| Lys 440 | Asn 440 | conflict |
| His 445 | Val 445 | conflict |
| Ser 446 | Gly 446 | conflict |
| Asp 450 | Asn 450 | conflict |
| Trp 452 | Leu 452 | conflict |
| Lys 460 | Asn 460 | conflict |
| Asn 477 | Ser 477 | conflict |
| Lys 478 | Thr 478 | conflict |
| Lys 481 | Asn 481 | conflict |
| - | Val 483 | deletion |
| Lys 483 | Glu 484 | conflict |
| Pro 485 | Phe 486 | conflict |
| Arg 497 | Gln 498 | conflict |
| Tyr 500 | Asn 501 | conflict |
| His 504 | Tyr 505 | conflict |
| Lys 553 | Glu 554 | conflict |
| Val 569 | Ala 570 | conflict |
| Gly 613 | Asp 614 | conflict |
| Ser 620 | Pro 621 | conflict |
| Tyr 654 | His 655 | conflict |
| Val 669 | Ile 670 | conflict |
| Lys 679 | Asn 679 | conflict |
| Arg 681 | Pro 681 | conflict |
| Gly 682 | Arg 682 | conflict |
| Ser 683 | Arg 683 | conflict |
| Ser 685 | Arg 685 | conflict |
| Lys 764 | Asn 764 | conflict |
| Tyr 796 | Asp 796 | conflict |
| Pro 817 | Phe 817 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Phe 939 | Ser 939 | conflict |
| Pro 942 | Ala 942 | conflict |
| His 954 | Gln 954 | conflict |
| Lys 969 | Asn 969 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
| Leu 1143 | Pro 1143 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 525496.2 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 5717.3 | |
| All* | Total formula weight | 531213.5 |
