8WY0

T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (a, b)	T-cell surface glycoprotein CD3 zeta chain	polymer	195	21809.7	2	UniProt (P20963) Pfam (PF11628) Pfam (PF02189)	Homo sapiens (human)	T-cell receptor T3 zeta chain
2	C (d)	T-cell surface glycoprotein CD3 delta chain	polymer	171	18949.5	1	UniProt (P04234) Pfam (PF16680) Pfam (PF02189)	Homo sapiens (human)	T-cell receptor T3 delta chain
3	D, E (e, f)	T-cell surface glycoprotein CD3 epsilon chain	polymer	207	23174.2	2	UniProt (P07766) Pfam (PF16681) Pfam (PF02189)	Homo sapiens (human)	T-cell surface antigen T3/Leu-4 epsilon chain
4	F (g)	T-cell surface glycoprotein CD3 gamma chain	polymer	182	20493.5	1	UniProt (P09693) Pfam (PF16680) Pfam (PF02189)	Homo sapiens (human)	T-cell receptor T3 gamma chain
5	G (m)	Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant	polymer	310	34331.5	1	UniProt (A0JD36) UniProt (B7Z8K6) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (human)
6	H (n)	Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1	polymer	332	37407.0	1	UniProt (P0CF51) UniProt (Q99603) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (human)
7	I (b)	CHOLESTEROL	non-polymer		386.7	1	Chemie (CLR)

Sequence modifications

a, b: 1 - 164 (UniProt: P20963)

PDB	External Database	Details
Ala 165	-	expression tag
Ala 166	-	expression tag
Ala 167	-	expression tag
Trp 168	-	expression tag
Ser 169	-	expression tag
His 170	-	expression tag
Pro 171	-	expression tag
Gln 172	-	expression tag
Phe 173	-	expression tag
Glu 174	-	expression tag
Lys 175	-	expression tag
Gly 176	-	expression tag
Gly 177	-	expression tag
Gly 178	-	expression tag
Ser 179	-	expression tag
Gly 180	-	expression tag
Gly 181	-	expression tag
Gly 182	-	expression tag
Ser 183	-	expression tag
Gly 184	-	expression tag
Gly 185	-	expression tag
Ser 186	-	expression tag
Ala 187	-	expression tag
Trp 188	-	expression tag
Ser 189	-	expression tag
His 190	-	expression tag
Pro 191	-	expression tag
Gln 192	-	expression tag
Phe 193	-	expression tag
Glu 194	-	expression tag
Lys 195	-	expression tag

m: -17 - 19 (PDB: 8WY0)
m: 20 - 115 (UniProt: A0JD36)

PDB	External Database	Details
Leu 116	-	linker
Gly 117	-	linker
Met 118	-	linker
Gly 119	-	linker
Gly 120	-	linker
Glu 121	-	linker
Tyr 122	-	linker
Thr 123	-	linker
Asp 124	-	linker
Lys 125	-	linker
Leu 126	-	linker
Ile 127	-	linker
Phe 128	-	linker
Gly 129	-	linker
Lys 130	-	linker
Gly 131	-	linker
Thr 132	-	linker
Arg 133	-	linker
Val 134	-	linker
Thr 135	-	linker
Val 136	-	linker
Glu 137	-	linker
Pro 138	-	linker
Arg 139	-	linker

m: 140 - 292 (UniProt: B7Z8K6)

PDB	External Database	Details
Ala 283	Phe 144	engineered mutation
Ala 290	Phe 151	engineered mutation
Ala 291	Phe 152	engineered mutation

n: -15 - 20 (PDB: 8WY0)
n: 21 - 122 (UniProt: Q99603)

PDB	External Database	Details
Ala 123	-	linker
Gln 124	-	linker
Gln 125	-	linker
Glu 126	-	linker
Leu 127	-	linker
Gly 128	-	linker
Lys 129	-	linker
Lys 130	-	linker
Ile 131	-	linker
Lys 132	-	linker
Val 133	-	linker
Phe 134	-	linker
Gly 135	-	linker
Pro 136	-	linker
Gly 137	-	linker
Thr 138	-	linker
Lys 139	-	linker
Leu 140	-	linker
Ile 141	-	linker
Ile 142	-	linker
Thr 143	-	linker

n: 144 - 316 (UniProt: P0CF51)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	201149.3
Non-Polymers*	Number of molecules	1
	Total formula weight	386.7
All*	Total formula weight	201535.9

*Water molecules are not included.