8WX5

Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Solute carrier family 15 member 4	polymer	600	64856.2	1	UniProt (Q8N697) Pfam (PF00854)	Homo sapiens (human)	Peptide transporter 4,Peptide/histidine transporter 1,hPHT1
2	B (B)	TASL (TASL-SLC15A4 fusion protein)	polymer	15	1776.9	1	UniProt (by SIFTS) (Q9HAI6)	Homo sapiens

Sequence modifications

A: 1 - 577 (UniProt: Q8N697)

PDB	External Database	Details
Gly 578	-	expression tag
Ser 579	-	expression tag
Ile 580	-	expression tag
Glu 581	-	expression tag
Gly 582	-	expression tag
Arg 583	-	expression tag
Ile 584	-	expression tag
Val 585	-	expression tag
Lys 586	-	expression tag
Asp 587	-	expression tag
Tyr 588	-	expression tag
Lys 589	-	expression tag
Asp 590	-	expression tag
Asp 591	-	expression tag
Asp 592	-	expression tag
Asp 593	-	expression tag
Lys 594	-	expression tag
His 595	-	expression tag
His 596	-	expression tag
His 597	-	expression tag
His 598	-	expression tag
His 599	-	expression tag
His 600	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66633.1
All*	Total formula weight	66633.1

*Water molecules are not included.