8WVT

Crystal structure of Lsd18 in complex with ligands

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Putative epoxidase LasC	polymer	488	52646.7	2	UniProt (B5M9L6)	Streptomyces lasalocidi
2	C, H (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	D, E, I, J (A, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	4	Chemie (DMS) PubChem (679)
4	F (A)	(4R,5S)-3-((2R,3S,4S,E)-2,6-diethyl-9-((2R,3R)-2-ethyl-3-methyloxiran-2-yl)-3-hydroxy-4-methylnon-6-enoyl)-4-methyl-5-phenyloxazolidin-2-one	non-polymer		485.7	1	Chemie (X9E)
5	G, L (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL) PubChem (312)
6	K (B)	(4R,5S)-4-methyl-5-phenyl-3-((2R,3S,4S,6E,10E)-2,6,10-triethyl-3-hydroxy-4-methyldodeca-6,10-dienoyl)oxazolidin-2-one	non-polymer		469.7	1	Chemie (A1LWM)
7	M, N (A, B)	water	water		18.0	806	Chemie (HOH)

Sequence modifications

A, B: 17 - 488 (UniProt: B5M9L6)

PDB	External Database	Details
Met 1	-	initiating methionine
Asn 2	-	expression tag
His 3	-	expression tag
Lys 4	-	expression tag
Val 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
Ile 12	-	expression tag
Glu 13	-	expression tag
Gly 14	-	expression tag
Arg 15	-	expression tag
His 16	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	105293.4
Non-Polymers*	Number of molecules	10
	Total formula weight	2909.8
All*	Total formula weight	108203.2

*Water molecules are not included.