8WTJ

XBB.1.5.70 spike protein in complex with ACE2

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1317	145812.4	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	D (E)	Processed angiotensin-converting enzyme 2	polymer	594	68804.3	1	UniProt (Q9BYF1) Pfam (PF01401)	Homo sapiens (human)

Sequence modifications

A, B, C: 1 - 1204 (UniProt: P0DTC2)

PDB	External Database	Details
Ile 19	Thr 19	variant
-	Leu 24	deletion
-	Pro 25	deletion
-	Pro 26	deletion
Ser 24	Ala 27	variant
Ala 80	Val 83	variant
Asp 139	Gly 142	variant
-	Tyr 144	deletion
Gln 142	His 146	variant
Glu 179	Gln 183	variant
Glu 209	Val 213	variant
Val 248	Gly 252	variant
His 335	Gly 339	variant
Thr 342	Arg 346	variant
Ile 364	Leu 368	variant
Phe 367	Ser 371	variant
Pro 369	Ser 373	variant
Phe 371	Ser 375	variant
Ala 372	Thr 376	variant
Asn 401	Asp 405	variant
Ser 404	Arg 408	variant
Asn 413	Lys 417	variant
Lys 436	Asn 440	variant
Pro 441	Val 445	variant
Ser 442	Gly 446	variant
Phe 451	Leu 455	conflict
Leu 452	Phe 456	variant
Lys 456	Asn 460	variant
Asn 473	Ser 477	variant
Lys 474	Thr 478	variant
Ala 480	Glu 484	variant
Pro 482	Phe 486	variant
Ser 486	Phe 490	variant
Arg 494	Gln 498	variant
Tyr 497	Asn 501	variant
His 501	Tyr 505	variant
Gly 610	Asp 614	variant
Tyr 651	His 655	variant
Lys 675	Asn 679	variant
His 677	Pro 681	variant
Gly 678	Arg 682	conflict
Ser 679	Arg 683	conflict
Ser 681	Arg 685	conflict
Lys 760	Asn 764	variant
Tyr 792	Asp 796	variant
Pro 813	Phe 817	conflict
Thr 825	Ala 829	conflict
Lys 832	Gln 836	conflict
Pro 888	Ala 892	conflict
Pro 895	Ala 899	conflict
Pro 938	Ala 942	conflict
His 950	Gln 954	variant
Lys 965	Asn 969	variant
Pro 982	Lys 986	engineered mutation
Pro 983	Val 987	engineered mutation

A, B, C: 1205 - 1317 (PDB: 8WTJ)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	506241.6
All*	Total formula weight	506241.6

*Water molecules are not included.