8WS0

Crystal structure of human NEK7 S195D mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine/threonine-protein kinase Nek7	polymer	310	35698.1	2	UniProt (Q8TDX7) Pfam (PF00069)	Homo sapiens (human)	Never in mitosis A-related kinase 7,NimA-related protein kinase 7
2	C, D (A, B)	water	water		18.0	190	Chemie (HOH)

Sequence modifications

A, B: 1 - 302 (UniProt: Q8TDX7)

PDB	External Database	Details
Asp 195	Ser 195	engineered mutation
Leu 303	-	expression tag
Glu 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71396.2
All*	Total formula weight	71396.2

*Water molecules are not included.