8WQ5

Crystal structure of the C-terminal RRM domain of an RBP in complex with ssDNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	RNA-binding protein 45	polymer	116	13274.4	4	UniProt (Q8IUH3) Pfam (PF00076)	Homo sapiens (human)	Developmentally-regulated RNA-binding protein 1,RB-1,RNA-binding motif protein 45
2	E, F, G, H (E, F, G, H)	DNA (5'-D(*GP*AP*CP*GP*CP*AP*G)-3')	polymer	7	2147.4	4		Homo sapiens
3	I, J (B, D)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	636	Chemie (HOH)

Sequence modifications

A, B, C, D: 370 - 476 (UniProt: Q8IUH3)

PDB	External Database	Details
Met 369	-	initiating methionine
Leu 477	-	expression tag
Glu 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag
His 481	-	expression tag
His 482	-	expression tag
His 483	-	expression tag
His 484	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	61687.2
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	61871.3

*Water molecules are not included.